77779193永利-yl23455永利

    Background:  

    Rab3A is a small G-protein of the Rab family, that is implicated in vesicle fusion and regulated secretion, 

    particularly in neurotransmitter release. Rab3 subfamily small G proteins (Rab3A, Rab3B, Rab3C, and Rab3D) 

    control the regulated exocytosis in neuronal/secretory cells. Rab3A is the most abundant Rab GTPase in brain, 

    where it is associated with synaptic vesicles. Rab3A is believed to modulate secretion efficiency by stimulating 

    vesicle recruitment to sites of exocytosis and/ or by recruiting regulatory molecules to the docking/ fusion machinery.