77779193永利-yl23455永利

    Background:  

    The human RAB genes share structural and biochemical properties with the Ras gene superfamily, and RAB4 

    (synonym: RAB4A) is a small GTPase belonging to this Ras superfamily. Accumulating data suggests an important 

    role for RAB proteins either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized 

    proteins from endoplasmic reticulum to the Golgi complex and to secretory vesicles involves the movement of carrier

    vesicles, a process that appears to involve RAB protein function. RAB4 may also function as regulator along the 

    receptor  recycling pathway.