Product Uses Include
Analysis of in vivo Sar1A activation levels
Detection of compounds and proteins that enhance Sar1A activity
Detection of compounds and proteins that inhibit Sar1A activity
The activity of Sar1A in cells (tissues) was studied qualitatively
Product Description
| Description | Anti-Active Sar1A Mouse Monoclonal Antibody |
| Another Name | Anti-Sar1A-GTP Mouse Monoclonal Antibody |
| Catalog Number | NL23018 |
| Size: | 30 µl |
| Tested Applications: | IP , IF |
| Cited Applications: | IP , IHC , IF IHF |
| Tested Reactivity: | Human , mouse |
| Cited Reactivity: | Human , mouse Rat |
| Gene Symbol: | SAR1 |
| Immunogen : | Recombinant full length protein of active Sar1A |
| Concentration: | 1mg/ml |
| Host/Isotype: | mouse/IgG |
| Class: | monnoclonal |
| Type: | Antibody |
| Predicted mv: | 22KDa |
| Observed mv: | 22KDa |
| Uniprot: | Q9NR31 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
|
Background: |
SAR1A, also named as SAR1, SARA and SARA1, belongs to the small GTPase superfamily and SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus. SAR1A is required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP- dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). The antibody is specific to SAR1A.
|
Tested Applications: IP/WB
