Product Uses Include
Analysis of in vivo Rac1 activation levels
Detection of compounds and proteins that enhance Rac1 activity
Detection of compounds and proteins that inhibit Rac1 activity
The activity of Rac1 in cells (tissues) was studied qualitatively
Product Description
Description | Anti-Active Rac1 Mouse Monoclonal Antibody |
Another Name | Anti-Rac1-GTP Mouse Monoclonal Antibody |
Catalog Number | NL23001 |
Size: | 30 µl |
Tested Applications: | IP , IHF IHC |
Cited Applications: | IP , IHC , IF , FC ICC ICF IHF |
Tested Reactivity: | Human , mouse Rat |
Cited Reactivity: | Human , mouse Rat |
Gene Symbol: | RAC1 |
Immunogen : | Recombinant full length protein of active Rac1 |
Concentration: | 1mg/ml |
Host/Isotype: | mouse/IgM |
Class: | monnoclonal |
Type: | Antibody |
Predicted mv: | 21KDa |
Observed mv: | 21KDa |
Uniprot: | p63000 |
Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Storage Conditions: | Store at -20°C for one year after shipment |
Background: |
Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is ai ded by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors
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Tested Applications: IP/WB
Tested Applications: IHF
Tested Applications: IHC