Product Description
| Description | Anti-KRas (G12D) Mouse Monoclonal Antibody |
| Another Name | Anti-KRas (Mutated G12D) Mouse Monoclonal Antibody |
| Catalog Number | NL25091 |
| Size: | 100 µl |
| Tested Applications: | ELISA WB IF ELISA:1:500-1:1000 WB:1:500-1:1000 IF:1:50-1:200 |
| Cited Applications: | WB IF |
| Tested Reactivity: | Human , mouse Rat |
| Cited Reactivity: | Human , mouse Rat |
| Gene Symbol: |
CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; NS; NS3; OES; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; ' C-K-RAS; c-Ki-ras; c-Ki-ras2; NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1 |
| Immunogen : | A synthetic peptide from the internal region of KRas which includes the mutation of G12D, human origin |
| Concentration: | 1mg/ml |
| Host/Isotype: | mouse/IgG1,IgG2a ,IgG2b |
| Class: | monnoclonal |
| Type: | Antibody |
| Predicted mv: | 21 KDa |
| Observed mv: | 21 KDa |
| Uniprot: | P01116 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
|
Background: |
Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in decreased GTPase activity and constitutive signaling. This mutation is found in many types of human cancers.
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Tested Applications: WB
Tested Applications: IF
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