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| 价格： | 特价:600 |
| 品牌： | NEWLF  |
| 货号： | NL25071 |
| 规格： | 100ul |
Product Description
| Description | Anti-Ric8A Mouse Monoclonal Antibody |
| Another Name | Anti-Ric8A Mouse Monoclonal Antibody |
| Catalog Number | NL25071 |
| Size: | 100 µl |
| Tested Applications: | ELISA WB ELISA:1:1000-1:5000 WB:1:500-1:2000 |
| Cited Applications: | ELISA WB |
| Tested Reactivity: | Human , mouse |
| Full Name | RIC8 guanine nucleotide exchange factor A |
| Gene Symbol: | RIC8 |
| Immunogen : | A synthetic peptide near the C-terminus of Ric-8A, human origin |
| Concentration: | 1mg/ml |
| Host/Isotype: | Mouse/IgG |
| Class: | Monoclonal |
| Type: | Antibody |
| Predicted mv: | 60 KDa |
| Observed mv: | 60 KDa |
| Uniprot: | Q9NPQ8 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
Background: | Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. |
Tested Applications: WB
