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| 价格： | ￥1600 |
| 品牌： | NEWLF  |
| 货号： | NL24003 |
| 规格： | 100ul |
Product Description
| Description | Anti-Cdc42 Rabbit Polyclonal Antibody |
| Another Name | Anti-Cdc42 Rabbit Polyclonal Antibody |
| Catalog Number | NL24003 |
| Size: | 100 µl |
| Tested Applications: | ELISA WB ELISA：1:1000-1:5000 WB: 1:1000-1:3000 |
| Cited Applications: | ELISA WB IHC |
| Tested Reactivity: | Human , mouse Rat |
| Full name: | cell division cycle 42 (GTP binding protein, 25kDa) |
| Gene Symbol: | CDC42, CDC42Hs, G25K, G25K GTP binding protein |
| Immunogen : | Fusion protein of human CDC42 |
| Concentration: | 1mg/ml |
| Host/Isotype: | Rabbit/IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Predicted mv: | 21KDa |
| Observed mv: | 21KDa |
| Uniprot: | p60953 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
Background: | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. |
Tested Applications: WB
