Product Uses Include
Analysis of in vivo Arf6 activation levels
Detection of compounds and proteins that enhance Arf6 activity
Detection of compounds and proteins that inhibit Arf6 activity
The activity of Arf6 in cells (tissues) was studied qualitatively
Product Description
Description | Anti-Active Arf6 Mouse Monoclonal Antibody |
Another Name | Anti-Arf6-GTP Mouse Monoclonal Antibody |
Catalog Number | NL23008 |
Size: | 30 µl |
Tested Applications: | IP , IHF |
Cited Applications: | IP , IHC , IF IHF |
Tested Reactivity: | Human , mouse |
Cited Reactivity: | Human , mouse Rat |
Gene Symbol: | ARF6 |
Immunogen : | Recombinant full length protein of active Arf6 |
Concentration: | 1mg/ml |
Host/Isotype: | mouse/IgG |
Class: | monnoclonal |
Type: | Antibody |
Predicted mv: | 21KDa |
Observed mv: | 21KDa |
Uniprot: | p62330 |
Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Storage Conditions: | Store at -20°C for one year after shipment |
Background: |
The ARF6 is a small GTPase that locates at the PM, cytosol, and endosomal membranes. ARF6 functions by cycling between an active GTP-bound and inactive GDP-bound conformation. ARF6 regulates diverse cellular processes including exocytosis, endocytosis, endosomal recycling, and actin cytoskeleton remodeling, which underlines its important roles in cell motility, cell polarity, cell division, phagocytosis, and cholesterol homeostasis.
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Tested Applications: IP/WB
Tested Applications: IHF