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| 价格： | ￥4800.00 |
| 品牌： | NEWLF  |
| 货号： | NL23019 |
| 规格： | 30ul |
Product Uses Include
Analysis of in vivo ARL1 activation levels
Detection of compounds and proteins that enhance ARL1 activity
Detection of compounds and proteins that inhibit ARL1 activity
The activity of ARL1 in cells (tissues) was studied qualitatively
Product Description
| Description | Anti-Active ARL1 Mouse Monoclonal Antibody |
| Another Name | Anti-ARL1-GTP Mouse Monoclonal Antibody |
| Catalog Number | NL23019 |
| Size: | 30 µl |
| Tested Applications: | IP |
| Cited Applications: | IP , IHC , IF |
| Tested Reactivity: | Human , mouse |
| Cited Reactivity: | Human , mouse Rat |
| Gene Symbol: | ARL1 |
| Immunogen : | Recombinant full length protein of active ARL1 |
| Concentration: | 1mg/ml |
| Host/Isotype: | mouse/IgG |
| Class: | monnoclonal |
| Type: | Antibody |
| Predicted mv: | 20KDa |
| Observed mv: | 20KDa |
| Uniprot: | P40616 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
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Background: |
RALA belongs to the small GTPase superfamily. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. RALA plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. As an effector of the proto-oncogene Ras, it play an important role in the molecular pathology of human malignancies.
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Tested Applications: IP/WB
