Product Uses Include
Analysis of in vivo Rab3A activation levels
Detection of compounds and proteins that enhance Rab3A activity
Detection of compounds and proteins that inhibit Rab3A activity
The activity of Rab3A in cells (tissues) was studied qualitatively
Product Description
Description | Anti-Active Rab3A Mouse Monoclonal Antibody |
Another Name | Anti-Rab3A-GTP Mouse Monoclonal Antibody |
Catalog Number | NL23014 |
Size: | 30 µl |
Tested Applications: | IP , IF |
Cited Applications: | IP , IHC , IF |
Tested Reactivity: | Human , mouse |
Cited Reactivity: | Human , mouse Rat |
Gene Symbol: | RAB3A |
Immunogen : | Recombinant full length protein of active Rab3A |
Concentration: | 1mg/ml |
Host/Isotype: | mouse/IgG |
Class: | monnoclonal |
Type: | Antibody |
Predicted mv: | 25KDa |
Observed mv: | 25KDa |
Uniprot: | P20336 |
Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Storage Conditions: | Store at -20°C for one year after shipment |
Background: |
Rab3A is a small G-protein of the Rab family, that is implicated in vesicle fusion and regulated secretion, particularly in neurotransmitter release. Rab3 subfamily small G proteins (Rab3A, Rab3B, Rab3C, and Rab3D) control the regulated exocytosis in neuronal/secretory cells. Rab3A is the most abundant Rab GTPase in brain, where it is associated with synaptic vesicles. Rab3A is believed to modulate secretion efficiency by stimulating vesicle recruitment to sites of exocytosis and/ or by recruiting regulatory molecules to the docking/ fusion machinery.
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Tested Applications: IP/WB
Tested Applications: IF