Anti-Active Rab3A Mouse Monoclonal Antibody

价格:¥4800.00
品牌:NEWLF   
货号:NL23014
规格:30ul

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  • 概述

    Product Uses Include  

         

         Analysis of in vivo Rab3A activation levels

          Detection of compounds and proteins that enhance Rab3A activity

          Detection of compounds and proteins that inhibit Rab3A activity

          The activity of Rab3A  in cells (tissues) was studied qualitatively

     

    Product  Description

     

       Description     Anti-Active Rab3A  Mouse  Monoclonal Antibody
       Another Name     Anti-Rab3A-GTP    Mouse  Monoclonal Antibody        
       Catalog Number     NL23014
       Size:      30 µl
       Tested Applications:       IP , IF  
       Cited  Applications:     IP , IHC , IF   
       Tested Reactivity:      Human , mouse   
       Cited  Reactivity:        Human , mouse   Rat
       Gene Symbol:       RAB3A
       Immunogen :       Recombinant full length protein of active Rab3A
       Concentration:                 1mg/ml
       Host/Isotype:                      mouse/IgG
       Class:                    monnoclonal
       Type:                                   Antibody
       Predicted mv:                      25KDa
       Observed mv:                  25KDa
       Uniprot:                               P20336
       Constituents:       PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
       Storage Conditions:        Store at -20°C for one year after shipment

      

        Background:  

        Rab3A is a small G-protein of the Rab family, that is implicated in vesicle fusion and regulated secretion, 

        particularly in neurotransmitter release. Rab3 subfamily small G proteins (Rab3A, Rab3B, Rab3C, and Rab3D) 

        control the regulated exocytosis in neuronal/secretory cells. Rab3A is the most abundant Rab GTPase in brain, 

        where it is associated with synaptic vesicles. Rab3A is believed to modulate secretion efficiency by stimulating 

        vesicle recruitment to sites of exocytosis and/ or by recruiting regulatory molecules to the docking/ fusion machinery.

     


     

     

     

    Tested Applications:  IP/WB

     

                

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    Tested Applications:  IF

     

     

                       

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