Anti-Active Rac1 Mouse Monoclonal Antibody

价格:¥4800.00
品牌:NEWLF   
货号:NL23001
规格:30ul

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  • 概述

    Product Uses Include  

         

         Analysis of in vivo Rac1 activation levels

          Detection of compounds and proteins that enhance Rac1 activity

          Detection of compounds and proteins that inhibit Rac1 activity

          The activity of Rac1 in cells (tissues) was studied qualitatively

     

    Product  Description

     

       Description     Anti-Active Rac1 Mouse Monoclonal Antibody
       Another Name     Anti-Rac1-GTP   Mouse  Monoclonal Antibody
       Catalog Number     NL23001
       Size:      30 µl
       Tested Applications:       IP , IHF  IHC
       Cited  Applications:     IP , IHC , IF , FC  ICC  ICF  IHF
       Tested Reactivity:      Human , mouse   Rat
       Cited  Reactivity:        Human , mouse   Rat
       Gene Symbol:       RAC1
       Immunogen :       Recombinant full length protein of active Rac1
       Concentration:                 1mg/ml
       Host/Isotype:                      mouse/IgM
       Class:                    monnoclonal
       Type:                                   Antibody
       Predicted mv:                      21KDa
       Observed mv:                  21KDa
       Uniprot:                               p63000
       Constituents:       PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
       Storage Conditions:        Store at -20°C for one year after shipment

      

        Background:  

        Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that 

        regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis 

        of GTP to GDP renders it inactive. GTP  hydrolysis is ai  ded by GTPase activating proteins (GAPs), while  exchange of

        GDP for GTP is facilitated by guanine nucleotide exchange  factors 

     


     

     

     

    Tested Applications:  IP/WB

     

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    Tested Applications:  IHF

     

     

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    Tested Applications: IHC

     

     

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