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| 价格： | ￥4800.00 |
| 品牌： | NEWLF  |
| 货号： | NL23003 |
| 规格： | 30ul |
Product Uses Include
Analysis of in vivo Cdc42 activation levels
Detection of compounds and proteins that enhance Cdc42 activity
Detection of compounds and proteins that inhibit Cdc42 activity
The activity of Cdc42 in cells (tissues) was studied qualitatively
Product Description
| Description | Anti-Active Cdc42 Mouse Monoclonal Antibody |
| Another Name | Anti-Cdc42-GTP Mouse Monoclonal Antibody |
| Catalog Number | NL23003 |
| Size: | 30 µl |
| Tested Applications: | IP , IF |
| Cited Applications: | IP , IHC , IF , FC ICC ICF IHF |
| Tested Reactivity: | Human , mouse |
| Cited Reactivity: | Human , mouse Rat |
| Gene Symbol: | Cdc42 |
| Immunogen : | Recombinant full length protein of active Cdc42 |
| Concentration: | 1mg/ml |
| Host/Isotype: | mouse/IgG1 |
| Class: | monnoclonal |
| Type: | Antibody |
| Predicted mv: | 21KDa |
| Observed mv: | 21KDa |
| Uniprot: | p60953 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
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Background: |
Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs).
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Tested Applications: IP/WB
Tested Applications: IF