Anti- PIk3CA(Q546P) Mouse Monoclonal Antibody

价格:¥4080.00
品牌:NEWLF   
货号:NL25110
规格:100ul

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    Product  Description


       Description    Anti-PIK3CA (Q546P)  Mouse Monoclonal Antibody
       Another Name    Anti-PIK3CA (Mutated  Q546P) Mouse Monoclonal Antibody
       Catalog Number    NL25110
       Size:     100 µl
       Tested Applications:      ELISA  WB  IF  IHC        ELISA:1:500-1:1000       WB:1:500-1:1000      
       Cited  Applications:    WB  
       Tested Reactivity:     Human , mouse   Rat
       Cited  Reactivity:       Human , mouse   Rat
       Gene Symbol:  

        MCM; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha

       Immunogen :      A synthetic peptide from the internal region of human PIK3CA which includes the mutation of Q546P
       Concentration:                1mg/ml
       Host/Isotype:                     mouse/IgG
       Class:                   monnoclonal
       Type:                                  Antibody
       Predicted mv:                     124 KDa
       Observed mv:                  30 KDa
       Uniprot:                              P42336
       Constituents:      PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
       Storage Conditions:       Store at -20°C for one year after shipment

      

        Background:  

        Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. 

        The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns,

        PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. 

        A pseudogene of this gene has been defined on chromosome 22.





    Tested Applications:  WB

          


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