Product Description
Description | Anti-GNAQ(Q209L) Mouse Monoclonal Antibody |
Another Name | Anti-GNAQ(Mutated Q209L) Mouse Monoclonal Antibody |
Catalog Number | NL25119 |
Size: | 100 µl |
Tested Applications: | ELISA WB IF IHC ELISA:1:500-1:1000 WB:1:500-1:1000 IF:1:50-1:100 |
Cited Applications: | WB IF |
Tested Reactivity: | Human , mouse Rat |
Cited Reactivity: | Human , mouse Rat |
Gene Symbol: | GAQ; SWS; CMC1; G-ALPHA-q |
Immunogen : | A synthetic peptide from the internal region of human GNAQ which includes the mutation of Q209L |
Concentration: | |
Host/Isotype: | mouse/IgG |
Class: | monnoclonal |
Type: | Antibody |
Predicted mv: | 42KDa |
Observed mv: | 42 KDa |
Uniprot: | P50148 |
Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Storage Conditions: | Store at -20°C for one year after shipment |
Background: | This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2. |
Tested Applications: WB
Tested Applications: IF
The image is immunofluorescence of HEK293T cells transfected with pCDNA3-GFP GNAQ (mutated Q209L) plasmid pCDNA3-GFP GNAQ (WT) plasmid, pCDNA3-GFP GNAQ (mutated Q209P) plasmid or pCDNA3-GFP GNAQ (mutated Q209R) plasmid using NL25119 (GNAQ (mutated Q209L) Antibody) at dilution 1/50.