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| 价格： | ￥4480.00 |
| 品牌： | NEWLF  |
| 货号： | NL25096 |
| 规格： | 100ul |
Product Description
| Description | Anti-KRas (Q61L) Mouse Monoclonal Antibody |
| Another Name | Anti-KRas (Mutated Q61L) Mouse Monoclonal Antibody |
| Catalog Number | NL25096 |
| Size: | 100 µl |
| Tested Applications: | ELISA WB IF ELISA:1:500-1:1000 WB:1:500-1:1000 IF:1:50-1:200 |
| Cited Applications: | WB IF |
| Tested Reactivity: | Human , mouse Rat |
| Cited Reactivity: | Human , mouse Rat |
| Gene Symbol: | CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; NS; NS3; OES; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; ' C-K-RAS; c-Ki-ras; c-Ki-ras2; NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1 |
| Immunogen : | A synthetic peptide from the internal region of KRas which includes the mutation of Q61L, human origin |
| Concentration: | 1mg/ml |
| Host/Isotype: | mouse/IgG |
| Class: | monnoclonal |
| Type: | Antibody |
| Predicted mv: | 21 KDa |
| Observed mv: | 21 KDa |
| Uniprot: | P01116 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
Background: | Ras(Q61L) is one type of Ras missense mutations at codon 61,Ras protein is a membrane-associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival. Ras Q61L mutation result in decreased GTPase activity and constitutive signaling, and is correlated with the development of pancreatic intraepithelial neoplasia and lung lesions. |
Tested Applications: WB
Tested Applications: IF
Immunofluorescence of cells expressing Ras proteins with Anti-Ras(Q61L) antibody. HEK293T cells were transfected with pCDNA3-GFP-Ras(Q61L) plasmid, pCDNA3-GFP-Ras (WT) plasmid, pCDNA3-GFP-Ras (Q61H) plasmid, pCDNA3-GFP-Ras (Q61R) plasmid or pCDNA3-GFP-Ras (Q61K) plasmid, then fixed and stained with Anti-Ras(Q61L) monoclonal antibody (Cat. #NL25096).