Anti-HRas(A146T) Mouse Monoclonal Antibody

价格:¥4480.00
品牌:NEWLF   
货号:NL25097
规格:100ul

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    Product  Description


       Description    Anti-HRas (A146T)  Mouse Monoclonal Antibody
       Another Name    Anti-HRas (Mutated  A146T) Mouse Monoclonal Antibody
       Catalog Number    NL25097
       Size:     100 µl
       Tested Applications:      ELISA  WB  IF             ELISA:1:500-1:1000       WB:1:500-1:1000     IF:1:50-1:200      
       Cited  Applications:    WB  IF  
       Tested Reactivity:     Human , mouse   Rat
       Cited  Reactivity:       Human , mouse   Rat
       Gene Symbol:  

        CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; NS; NS3; OES; CFC2;

        RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; '

        C-K-RAS; c-Ki-ras; c-Ki-ras2; NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1

       Immunogen :      A synthetic peptide from the internal region of HRas which includes the mutation of A146T, human origin
       Concentration:                1mg/ml
       Host/Isotype:                     mouse/IgG
       Class:                   monnoclonal
       Type:                                  Antibody
       Predicted mv:                     21 KDa
       Observed mv:                 21 KDa
       Uniprot:                              P01116
       Constituents:      PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
       Storage Conditions:       Store at -20°C for one year after shipment

      

        Background:  

        The A146T mutation of KRas results in an amino acid substitution at position 146, from an alanine to a threonine. 

        KRAS encodes a protein that is a member of the small GTPase superfamily. Ras A146T mutation results in decreased

        GTPase activity and constitutive signaling. It can be found in many tumors, such as lung adenocarcinoma, mucinous 

        adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.





    Tested Applications:  WB


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    Tested Applications:  IF


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