返回
| 价格： | ￥3000.00 |
| 品牌： | NEWLF  |
| 货号： | NL25002-2 |
| 规格： | 100ul |
Product Description
| Description | Anti-cAMP Mouse Monoclonal Antibody |
| Another Name | Anti-cAMP Mouse Monoclonal Antibody |
| Catalog Number | NL25002-2 |
| Size: | 100 µl |
| Tested Applications: | ELISA WB IHC ELISA: 1:128000-1:512000 WB:1：1000- 1：2000 |
| Cited Applications: | ELISA WB IHC |
| Tested Reactivity: | Human , mouse Rat |
| Cited Reactivity: | Human , mouse Rat |
| Gene Symbol: | CAMP, CAP 18, CAP18, CRAMP, FALL 39, FALL39, hCAP 18, HSD26, LL37 |
| Immunogen : | Small Molecule, cAMP conjugated to BSA. |
| Concentration: | 1mg/ml |
| Host/Isotype: | mouse/IgG |
| Class: | monnoclonal |
| Type: | Antibody |
| Predicted mv: | 170 aa, 19 kDa |
| Observed mv: | 170 aa, 19 kDa |
| Uniprot: | P49913 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
|
Background: |
Adenosine 3, 5-cyclic monophosphate (cyclic AMP; cAMP) is one of the most important intracellular secondary messengers for transduction events. cAMP is also involved in regulating neuronal, glandular, cardiovascular, immune, and other functions and actions. A number of hormones, such as ACTH, TSH, FSH, and LH, are known to activate cAMP through the action of the enzyme adenylate cyclase, which converts ATP to cAMP. There remains considerable interest in the measurement of intracellular cAMP in tissues and cell cultures, and this may help to provide an understanding of the physiology and pathology of many disease states. Due to the involvement of cAMP in amplifying the response of ligand binding, the second messenger cAMP has been largely employed to monitor the activation of GPCR to facilitate therapeutic drug discovery.
|